At Bina, we are helping usher in a new era of medicine in which healthcare will change dramatically with customized treatments and data-driven insights tailored to the individual.
Today, cheap and fast sequencing is creating even more amounts of data that shows no signs of slowing. At Bina, we believe that the data-driven medicine of tomorrow will be powered by breakthrough innovations at the intersection of medical science and technology, yielding actionable insights in drug development, diagnosis, and treatment.
Personalized medicine promises to revolutionize the practice of medicine, transform the global healthcare industry, and ultimately lead to longer and healthier lives. The best and brightest minds in computer science and big data have come together at Bina to make good on that long-held promise.
We bridge DNA sequencing technologies with diagnosticians and clinicians, who can use genomic data to treat disease and save lives. We turn code into cures. Decoding the building blocks of life at the core of our technology.
Ultrafast, Accurate and Low-cost DNA Sequencing
Ever since the $3 billion and 13-year Human Genome Project jump-started a new industry in 1990, we have seen a revolution in DNA sequencing throughput and cost.
Today’s sequencing instruments not only perform the chemistry of sequencing, but also perform the initial conversion to raw sequenced data. Recent innovations in sequencing technologies have dramatically accelerated the time to sequence an entire genome to within a day, while lowering the cost of sequencing to within $1000 per genome.
Rapid, Low-cost and Accurate Secondary Analysis
Once a genome is sequenced, it must be assembled into a complete genome. Imagine putting together a billion-piece jigsaw puzzle. During secondary analysis, raw reads are assembled to form a complete genome and then the individual’s genetic variations, or single nucleotide variations (SNVs), are computed.
Connecting Genetic Mutations to Disease Causes
Completed genomes need to be interpreted for biological relevance, where mutations are matched with a certain disease or physical trait. It’s about finding the single nucleotide variations that have an impact on biological function and prescribing a treatment strategy. You’re literally looking for a needle in a haystack.
Medical Genetic Interpretation
Medical interpretation is combining sequencing data and the list of identified candidate mutations in a holistic manner with other medical factors, such as the patient’s history, environment, familial background, microbiome, diet, and more. Improving patient care and developing personalized therapies depends on intelligently leveraging complex molecular and clinical data from a variety of internal, external, and public sources.
Personalized Medicine: A New Standard of Care
We are ushering a new era of medicine, in which healthcare will change dramatically, with customized treatments tailored to the individual. There’s a huge opportunity right now at the intersection of high-performance computing, big data, and genomics. We at Bina are applying our interdisciplinary scientific skill sets towards building a world-changing technology. We are coding the cures of tomorrow.